Atrial natriuretic factor in human blood.

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Atrial natriuretic factor.

A short and up-to-date review on the great advances made in the field of the atrial natriuretic factor (ANF) is presented. All the short active peptides (up to 33 AA) isolated after purification of atrial homogenates have the same core of 23 amino acids (Ser 103-ARG 125). The ANF liberated in the medium of cultures of rat atrial cardiocytes is the 26 amino acid Arg 101-Tyr 126. Cloning of the c...

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Atrial natriuretic factor and the atrial function.

Accessible online at: http://BioMedNet.com/karger Dear Sir, I read with interest the report by Takeichi et al. [1] on the relationship between left atrial function and plasma levels of atrial natriuretic peptide in patients with various types of heart disease. I would like to make three comments. First, the term atrial natriuretic factor (ANF) is preferable to the term atrial natriuretic peptid...

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Partially purified human and rat atrial natriuretic factor.

Specific granules of rat atrial myocytes contain a potent fast-acting atrial natriuretic factor (ANF) and have been observed in all mammalian atria thus far examined. In this study, using a rat assay we found ANF in rat, rabbit, dog, baboon, and man. The ANF's from these species induced the characteristic diuresis and natriuresis of rapid onset and decay. The human and rat ANF's were acid-extra...

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The atrial natriuretic factor in hypertension.

Plasma immunoreactive atrial natriuretic factor (IR-ANF) concentration measured by radioimmunoassay after extraction on Sep-Pak cartridges was studied in 64 control normotensive subjects, 25 patients with labile essential hypertension, 67 patients with mild essential hypertension (diastolic pressure between 90 and 105 mm Hg and no left ventricular hypertrophy) and 9 patients with moderate to se...

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Effect of Extracellular Calcium Depletion on Atrial Natriuretic Factor Secretion and Gene Expression

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1985

ISSN: 0021-9738

DOI: 10.1172/jci112159